Polybrominated biphenyls and fetal mortality in Michigan.

Breast-feeding among women exposed to polybrominated biphenyls in Michigan.

In the early 1970s, the largest industrial accident in the United States resulted in widespread contamination of the food supply in Michigan with polybrominated biphenyls (PBBs). The chemical similarity of PBBs to compounds implicated as endocrine disruptors has raised the question of whether PBBs could affect the reproductive system. In the present analysis we examine the relation between seru...

Polybrominated biphenyls in lactating Michigan women: persistence in the population.

Polybrominated biphenyls (PBB) were inadvertently introduced into livestock feed in Michigan in 1973, resulting in widespread contamination of the state's food supply. Details of this unfortunate incident have been extensively documented (Carter 1976; Meester 1979). Approximately 12 months after the spill, several reports demonstrated the presence of PBB in human tissues including fat and blood...

Incidence of thyroid disease following exposure to polybrominated biphenyls and polychlorinated biphenyls, Michigan, 1974-2006.

Thyroid hormones, which influence body metabolism and development, could be affected by persistent organic pollutants. We sought to examine the relationship between polybrominated biphenyls (PBBs) and polychlorinated biphenyls (PCBs) and thyroid disease. We employed incidence density sampling to perform a nested case control analysis of the Michigan Long-Term PBB Cohort. Cohort members (n=3333)...

Carcinogenicity of polychlorinated biphenyls and polybrominated biphenyls.

Monograph Working Group Members V J Cogliano (USA)–Chair; K Aronson, H Tryphonas (Canada); Y L Guo (Taiwan, China); M Machala (Czech Republic); E C Bonefeld-Jørgensen, K Vorkamp (Denmark) J P Cravedi, B Le Bizec, J F Narbonne (France); H Esch (Germany); P Cocco, F Merletti (Italy); R Vermeulen (unable to attend; Netherlands); A Agudo (Spain); N Johansson (Sweden); H Fiedler, N Hopf (Switzerland...

Polybrominated biphenyls 74 Hazard assessment of Polybrominated biphenyls